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Know Your Mice

Housing and Environment
Mouse Genome
Temperature: 22 to 25C
R.H.: 50 to 70 percent
Light/Dark cycle: 14/10
Housing: Four adult mice per cage or: Breeders + litter
Number of chromosomes: 40
Diploid DNA content about 6 pg per cell
3x10 9 bp per haploid genome
Physiological Parameters
Breeding and Reproductive Data
Body temperature: 37 to 38C
Respiration rate: 94 to 163 per minute
Heart rate: 325 to 780 beats per minute
Water consumption: 3 to 7 ml per day
Urine excreted: 1 to 3 ml per day
Daily feed: 3 to 6 g per day
Blood volume: 70 to 80 ml/kg bodyweight
Blood collection: Max volume 0.5 to 0.7 percent of bodyweight
Breeding age: Six weeks
Cycle: Polyestrus four to five days when housed with a male
Mating: Place the female(s) into the male’s cage
Gestation: 19 to 21 days
Litter size: 6 to 12
Weaning age: 21 days
Optimal reproductive span: Seven to eight months
Other Information
  • Life span: 1.5 to 2.5 years.
  • Albinos have very poor eyesight due to degenerative retinas.
  • High sensitivity to water loss.
  • No sweat glands, can’t pant, poor salivation and can’t vomit.
  • Lose heat from ears and tail.
  • One lung lobe on the left and four on the right.
  • Male mice have 50 percent more spleenic tissue than females.
  • The tail is very sensitive to pain and is used in balance and as a thermoregulatory organ.